I tried the Skip 1s to control my devices, but it's not usable for now:
Apple TV 4K : not working, light on the Apple TV is telling it's receiving something but not working at all.
TV Set-Top Box: Amino Kamai 7x : Not working
HDMI Switch: Ultra HD HDMI2.ObMatrix 4K X 2K HDR ARC HIFI : Not Working, there is no possibility at all to select a HDMI Switch.
Onkyo HT-R340 Amplifier: this is working, but had to configure on/off by hand
Only Thing which is 100% working is My Samsung TV
Hope this will be change in the Future, for now I'm using a Logitech Hub, which is controlling everything 100%, but will be unsupported.
