In my system, the Flirc GUI indicated that it knew when the Flirc was connected and disconnected, but in over three weeks of trying various options, I was not consistently able to get it to recognize signals from my remote.
I have exactly the same problem. Oddly, when I first installed the software under Win 10, these options were available. I didn't select any at the time because I didn't yet understand what they did. Now they are dimmed and unavailable as in the OP's screen cap