Didn't you mention if you put the computer to sleep with the suspend key on the remote control, it will wake it up again? How are you putting your computer to sleep? You should be able to tell your computer which modes to go into as mentioned in that thread: http://cl.flirc.io/jIC2 I would try all those sleep modes.
Ugh, it's gotta be windows. If I can't even tell the computer that the device disappeared, nothing is going to work. Something is stopping all recognition from my device in windows. Why your logitech has anything to do with it, it's beyond me. Do you have any logitech software installed?
You aren't waisting my time at all. Lot of flircs get sold, this is going to be a big issue. There is one more thing I can try. Which is to emulate a disconnect. After your computer is sleeping, could you unplug flirc and plug it back in and see if the machine wakes up? I don't particularly like this, as it's not following the standard. I think it's hardware related. Are both computers identical in hardware? A lot of folks point back to the intel gpu on the threads. How about the control panel option I pointed to previously?
You know what, it looks like a fairly big problem with windows 10. Look at this: https://www.windows10forums.com/threads/cannot-wake-up-windows-10-from-sleep-with-external-mouse-and-keyboard.9674/ Go to the bottom and look at similar threads. There are dozens. There is an interesting post here: http://cl.flirc.io/jGvO On all the hubs, you can uncheck: "Allow the computer to turn off this device to save power" Also, a lot of people are pointing towards video drivers. What's in your system?